Gary has a rare tumour lodged in his spine. Leaving it in place will probably lead to paralysis, but an operation carries a huge risk. Margaret has developed a spontaneous hole in her skull.

Gary has a rare tumour lodged in his spine. Leaving it in place will probably lead to paralysis, but an operation carries a huge risk. Margaret has developed a spontaneous hole in her skull.

A risky operation on a 66-year-old's massive aortic aneurism, a complicated procedure to remove an angiosarcoma, and an operation which carries a significant risk of facial paralysis.

A risky operation on a 66-year-old's massive aortic aneurism, a complicated procedure to remove an angiosarcoma, and an operation which carries a significant risk of facial paralysis.

Laura, 29, has an incurable brain tumour. To extend her life, she needs it removed. But the hugely risky surgery will have a drastic effect on her memory and may even kill her.

Laura, 29, has an incurable brain tumour. To extend her life, she needs it removed. But the hugely risky surgery will have a drastic effect on her memory and may even kill her.

If surgeons don't operate on Pratyush soon, his tumour could push him into a coma, before killing him. Mariella needs a ground-breaking procedure for a recurring bowel cancer.

If surgeons don't operate on Pratyush soon, his tumour could push him into a coma, before killing him. Mariella needs a ground-breaking procedure for a recurring bowel cancer.

Following a liver transplant, an operation to remove a rare cancer of the soft palette, and a particularly nasty open fracture of a woman's lower leg.

Following a liver transplant, an operation to remove a rare cancer of the soft palette, and a particularly nasty open fracture of a woman's lower leg.

Stephen has highly aggressive jaw cancer and undergoes ground-breaking surgery to save his life. Hilary is suffering from a rare carcinoid tumour and faces a complex procedure with a 40% risk of death.

Stephen has highly aggressive jaw cancer and undergoes ground-breaking surgery to save his life. Hilary is suffering from a rare carcinoid tumour and faces a complex procedure with a 40% risk of death.